| Block 5 | Team #1 | Players/Picks Received | Team #2 | Players/Picks Received |
| ADR | Bowden Francis | NOT | 4th 2025 | |
| SFL | Waive: Andrew Knizer & Joey Wendle | SFL | Claim: Sam Haggerty & Chris Devenski | |
| SHS | Brandon Belt | MCG | Keegan Allen | |
| BBS | Luis Campusano | MUN | Yu Chang & Yanquiel Fernandez, ML1 | |
| MGC | Rafael Devers, Jake Bauers, Josh Palacios, NWT #3 | NWT | Freddie Freeman, Ryan McMahon, Lars Nootbaar | |
| MGC | Chris Sale, Miguel Castro, Shintaro Fujinami, Josh Sborz | CAC | Ryan Brasier, Chris Martin, Langeliers, and Jordan Montgomery | |
| OHJ | Luis Robert, Luke Raley, Jake Burger, J Donaldson, J.Rogers,D Dunning | MGC | Emmanuel Clase, Manny Machado, Cedric Mullins, John King, DeJong, Houser | |
| MER | Matt Moore | NOW | 5th ’25 | |
| MER | Release: Peter Strzelecki | |||
| CAC | James Outman | NOW | Robert Suarez | |
| MUN | Release: Jaime Barria & Nick Gordon | Mun | Claim: Luis Garcia (RP) & Evan Longoria | |
| BBS | Jose Leclerc | NWT | 5th ’25 | |
| NWT | Claim Drew Smith | |||
| BBS | Waive Kyle Wright | |||
| ARD | Waive: John Brebbia, Bryan Shaw, George Soriano | ARD | Claim: Alfonso Rivas, Billy McKinney | |
| Block 4 | OHJ | Zack Gelof, Josiah Gray, Tim Mayza, and Randy Vasquez | MUN | Jose Caballero, Trevor Larnach, Kyle Manzardo, Cionel Perez, and Spencer Turnbull |
| MOE | waive: Austin Cox, Trent Thorton | Claim: claim: Yerry De Los Santos | ||
| NOW: | waive: Trevor Story | |||
| SFL | Waive: Anthony DeScalfini | Claim: Andrew Knizer | ||
| NWT | Gavin Stone and Drew Smyly | MOE | Kyle Hendricks and Camilo Doval | |
| MUN | Paul Blackburn, MOE #5 ’25 | MOE | Edward Oliveras and Julio Urias | |
| MUN | Parker Meadows | SFL | Geraldo Perdomo | |
| MER | Waive: Sam Haggerty | MER | Claim: Peter Strzelecki | |
| NOW | ARD #4 ’25 | ARD | Bowden Francis | |
| SHS | Marcus Semien | NOW | SHS #2 ’25 and Brandon Drury | |
| MCG | NOW #5 ’25, Christian Yelich | NOW | MGC #2 ’25 and Steven Okert | |
| MUN | Claim: Aledmys Diaz | |||
| Block 3 | SFL | waive: Genesis Cabrera | SFL | claim: Luke Jackson |
| NOW | #1 ’25, Trevor Story, Ryan O’hearn | MGC | Freddie Freeman | |
| MER | Waive Caleb Theilbar | MER | claim Conner Capel | |
| ACR | Paul Sewald | NOT | Nate Pearson | |
| MER | waive: Caleb Theilbar | MER | Claim: Conner Capel | |
| ACR | Christian Encarnacion | MUN | David Festa and Everson Pereira | |
| MGC | Zack Gallen, Steve Okert | CHH | Max Fried, Gregory Santos | |
| Block 2 | NWT | #1 25 | SFL | Randy Arozarena |
| NWT | Waive: Dominic Canzone | NWT | Claim: | |
| OHJ | TJ Friedl, Daniel Coulombe #6 2025 | MOE | AJ Puk, Martin Maldanado #3 2025 | |
| TUV | #2 and # 7 2025 picks | OHJ | JD Martinez | |
| MOE | Waive: Martin Maldanado | MOE | Claim: | |
| MOE | Jake Cronenworth | SPC | Brendan Rogers | |
| OHJ | Waive: Kevin Pillar | |||
| Block 1 | TUV | Waive Isaiah Campbell | TUV | Claim – Chad Wallach |
| MOE | Waive- Tucker Barnhardt | MOE | Claim- Austin Cox | |
| Preseason | ANR | Mike Trout | OHJ | Cedric Mullins, Emmanuel Clase, ANR ’25 #2 |
| MGC | Jordan Montgomery, Chris Martin, Trekkers NWT ’25 #8 | NWT | Brock Wilken ML1, Adam Wainwright, Kris Bryant, MGC ’25 #2 | |
| WHS | Jorge Soler, NWT ’25 #11 | NWT | Dylan Lesko ML1, WHS ’25 #1 | |
| WHS | Lucas Sims | HEH | JD Davis | |
| MGC | Nicky Lopez OHJ ’25 #1 | OHJ | Dansby Swanson | |
| TUV | Blake Snell | MUN | TUV ’25 #1, Sebastian Walcott ML1, Cole Irwin, Jamie Barria | |
| MER | Waive Michael Vargas | |||
| MUN | Waive Brock Burke | |||
| WHS | Waive Andre Pallante | |||
| OHJ | Waive Kevin Pillar | |||
| CHH | Waive Taylor Clarke | |||
| CHH | Claim Jose Abreu | |||
| TUV | Claim Ian Campbell | |||
| ANR | Claim Huascar Brazoban | |||
| MER | Claim: Rafeal Tapia | |||
| NWT | Claim – CJ Cron | |||